Roles of aquaporin-4 and Kir4.1 in brain water and potassium homeostasis : lessons from knockout mice
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Abstract
No abstract.List of papers
Paper I: Haj-Yasein NN, Jensen V, Vindedal GF, Gundersen GA, Klungland A, Ottersen OP, Hvalby O, Nagelhus EA. Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human Kir4.1 gene (KCNJ10). Glia. 2011 Nov;59(11):1635-42. Epub 2011 Jul 11. The paper is removed from the thesis in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1002/glia.21205 |
Paper II: Haj-Yasein NN, Jensen V, Østby I, Omholt S, Voipio J, Kaila K, Ottersen OP, Hvalby Ø, Nagelhus EA. Aquaporin-4 regulates extracellular space volume dynamics during high-frequency synaptic stimulation: a gene deletion study in mouse hippocampus. Submitted. Glia. 2012, Online Early View. Epub 2012 Mar 14. The published version of this paper is available at: https://doi.org/10.1002/glia.22319 |
Paper III: Eilert-Olsen M, Haj-Yasein NN, Vindedal GF, Enger R, Gundersen GA, Hoddevik EH, Petersen PH, Haug FM, Skare Ø, Adams ME, Froehner SC, Burkhardt JM, Thoren AE, Nagelhus EA. Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier. Glia. 2012 Mar;60(3):432-40. Epub 2011 Nov 30. The published version of this paper is available at: https://doi.org/10.1002/glia.22277 |
Paper IV: Haj-Yasein NN, Vindedal GF, Eilert-Olsen M, Gundersen GA, Skare Ø, Laake P, Klungland A, Thorén AE, Burkhardt JM, Ottersen OP, Nagelhus EA. Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17815-20. Epub 2011 Oct 11. The paper is removed from the thesis in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1073/pnas.1110655108 |